Menopause Hormone Therapy (HRT) in Greensboro, NC

Bioidentical hormones in Greensboro: what it means

Behind the label "bioidentical hormone replacement therapy" is a plain idea: a hormone whose structure matches the body's own. Estradiol and micronized progesterone are both bioidentical: their structure matches the hormones the ovaries make. Neither has to be compounded: FDA-approved estradiol comes as pills, patches, gels, sprays, vaginal creams and rings, and progesterone as capsules.

"BHRT" often means compounded hormones, a cream, a blend such as Bi-Est or a pellet that a pharmacy mixes for one prescription. They are not FDA-approved, which means the FDA cannot assure their safety or effectiveness. The FDA says it has no evidence that compounded "bioidentical hormones" are safe and effective, or more effective than FDA-approved hormone therapy. The National Academies, reviewing them for the FDA in 2020, called their wide use a public health concern.

For women in Greensboro, a physician licensed in North Carolina can prescribe estradiol (pill, patch, cream or vaginal) and progesterone when they fit your history. There are no pellets. The pharmacy that fills VevaMD prescriptions also compounds, so ask your physician whether yours is an FDA-approved product or compounded. Two options are compounded for certain: testosterone cream for women and Bi-Est are not FDA-approved.

For its size, Greensboro is well supplied with OB-GYNs: the NPI registry lists 84, or 28.1 per 100,000 residents, against 17.8 for the US and above North Carolina's 18.9. Set against the city's 36,197 women aged 45 to 64, that is one OB-GYN for roughly every 430.

Supply stays thin beyond the city line: 84 OB-GYNs within 10 miles and 136 within 25, only 13.8 per 100,000 of the 986,703 people who live in that radius, under the US 17.8. VevaMD is an online option alongside them: a physician licensed in North Carolina reviews your intake from Greensboro without an office visit, and an OB-GYN you already see stays your doctor.

Then there are pellets, implanted under the skin at a clinic; compounded pellets are not FDA-approved. The Endocrine Society points to a study that found hormone levels well above the expected range in women using them. ACOG recommends FDA-approved menopause hormone therapy over compounded hormones.

Sources: FDA: Menopause · FDA: National Academies study of compounded bioidentical hormones (2020) · Endocrine Society position statement on compounded bioidentical hormones (2019) · ACOG Clinical Consensus No. 6, compounded bioidentical menopausal hormone therapy (2023) · CMS NPPES NPI full file, 2026-10-11